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PDIA3 gene induces visceral hypersensitivity in rats with irritable bowel syndrome through the dendritic cell-mediated activation of T cells

This study investigated the mechanism of protein disulfide-isomerase A3 (PDIA3)-induced visceral hypersensitivity in irritable bowel syndrome (IBS). Rats were treated with saline (control), acetic acid and restraint stress (IBS model), empty vector (RNAi control) and PDIA3-RNAi vector (PDIA3-RNAi)....

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Detalles Bibliográficos
Autores principales:	Zhuang, Zhaomeng, Zhang, Lu, Wang, Xiaoteng, Tao, Liyuan, Lv, Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2016
Materias:	Allergy and Clinical Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119228/ https://www.ncbi.nlm.nih.gov/pubmed/27896022 http://dx.doi.org/10.7717/peerj.2644

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