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Ligation of CD40 in Human Müller Cells Induces P2X(7) Receptor–Dependent Death of Retinal Endothelial Cells
PURPOSE: Cluster of differentiation 40 (CD40) is required for retinal capillary degeneration in diabetic mice, a process mediated by the retinal endothelial cells (REC) death. However, CD40 activates prosurvival signals in endothelial cells. The purpose of this study was to identify a mechanism by w...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119488/ https://www.ncbi.nlm.nih.gov/pubmed/27893093 http://dx.doi.org/10.1167/iovs.16-20301 |