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Deferred radiotherapy and upfront procarbazine–ACNU–vincristine administration for 1p19q codeleted oligodendroglial tumors are associated with favorable outcome without compromising patient performance, regardless of WHO grade
Recently updated phase III trials revealed the favorable effect of add-on procarbazine-lomustine-vincristine chemotherapy (CT) to radiotherapy (RT) in treating anaplastic oligodendrogliomas with 1p19q codeletion (codel). However, the underlying rationality of deferring RT and upfront CT administrati...
Autores principales: | Hata, Nobuhiro, Yoshimoto, Koji, Hatae, Ryusuke, Kuga, Daisuke, Akagi, Yojiro, Suzuki, Satoshi O, Iwaki, Toru, Shono, Tadahisa, Mizoguchi, Masahiro, Iihara, Koji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119620/ https://www.ncbi.nlm.nih.gov/pubmed/27895504 http://dx.doi.org/10.2147/OTT.S115911 |
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