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Efficacy and safety of talimogene laherparepvec versus granulocyte-macrophage colony-stimulating factor in patients with stage IIIB/C and IVM1a melanoma: subanalysis of the Phase III OPTiM trial

OBJECTIVES: Talimogene laherparepvec is the first oncolytic immunotherapy to receive approval in Europe, the USA and Australia. In the randomized, open-label Phase III OPTiM trial (NCT00769704), talimogene laherparepvec significantly improved durable response rate (DRR) versus granulocyte-macrophage...

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Detalles Bibliográficos
Autores principales:	Harrington, Kevin J, Andtbacka, Robert HI, Collichio, Frances, Downey, Gerald, Chen, Lisa, Szabo, Zsolt, Kaufman, Howard L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119624/ https://www.ncbi.nlm.nih.gov/pubmed/27895500 http://dx.doi.org/10.2147/OTT.S115245

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