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K63-Linked Ubiquitination Targets Toxoplasma gondii for Endo-lysosomal Destruction in IFNγ-Stimulated Human Cells
Toxoplasma gondii is the most common protozoan parasitic infection in man. Gamma interferon (IFNγ) activates haematopoietic and non-haematopoietic cells to kill the parasite and mediate host resistance. IFNγ-driven host resistance pathways and parasitic virulence factors are well described in mice,...
Autores principales: | Clough, Barbara, Wright, Joseph D., Pereira, Pedro M., Hirst, Elizabeth M., Johnston, Ashleigh C., Henriques, Ricardo, Frickel, Eva-Maria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119857/ https://www.ncbi.nlm.nih.gov/pubmed/27875583 http://dx.doi.org/10.1371/journal.ppat.1006027 |
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