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Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes
In eukaryotes, accurate protein synthesis relies on a family of translational GTPases that pair with specific decoding factors to decipher the mRNA code on ribosomes. We present structures of the mammalian ribosome engaged with decoding factor⋅GTPase complexes representing intermediates of translati...
Autores principales: | Shao, Sichen, Murray, Jason, Brown, Alan, Taunton, Jack, Ramakrishnan, V., Hegde, Ramanujan S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119991/ https://www.ncbi.nlm.nih.gov/pubmed/27863242 http://dx.doi.org/10.1016/j.cell.2016.10.046 |
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