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Human Neural Stem Cell Transplantation Rescues Cognitive Defects in APP/PS1 Model of Alzheimer’s Disease by Enhancing Neuronal Connectivity and Metabolic Activity
Alzheimer’s disease (AD), the most frequent type of dementia, is featured by Aβ pathology, neural degeneration and cognitive decline. To date, there is no cure for this disease. Neural stem cell (NSC) transplantation provides new promise for treating AD. Many studies report that intra-hippocampal tr...
Autores principales: | Li, Xueyuan, Zhu, Hua, Sun, Xicai, Zuo, Fuxing, Lei, Jianfeng, Wang, Zhanjing, Bao, Xinjie, Wang, Renzhi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120101/ https://www.ncbi.nlm.nih.gov/pubmed/27932977 http://dx.doi.org/10.3389/fnagi.2016.00282 |
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