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The Generalized Relative Pairs IBD Distribution: Its Use in the Detection of Linkage

I introduce a novel approach to derive the distribution of disease affectional status given alleles identical by descent (IBD) sharing through ITO method. My approach tremendously simplifies the calculation of the affectional status distribution compared to the conventional method, which requires th...

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Detalles Bibliográficos
Autor principal: Zou, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120125/
https://www.ncbi.nlm.nih.gov/pubmed/27933287
http://dx.doi.org/10.3389/fpubh.2016.00259