Functional Interplay Between Murine Leukemia Virus Glycogag, Serinc5, and Surface Glycoprotein Governs Virus Entry, with Opposite Effects on Gammaretroviral and Ebolavirus Glycoproteins

Gammaretroviruses, such as murine leukemia viruses (MLVs), encode, in addition to the canonical Gag, Pol, and Env proteins that will form progeny virus particles, a protein called “glycogag” (glycosylated Gag). MLV glycogag contains the entire Gag sequence plus an 88-residue N-terminal extension. It...

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Detalles Bibliográficos
Autores principales: Ahi, Yadvinder S., Zhang, Shu, Thappeta, Yashna, Denman, Audrey, Feizpour, Amin, Gummuluru, Suryaram, Reinhard, Bjoern, Muriaux, Delphine, Fivash, Matthew J., Rein, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120145/
https://www.ncbi.nlm.nih.gov/pubmed/27879338
http://dx.doi.org/10.1128/mBio.01985-16

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