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Aire Downregulation Is Associated with Changes in the Posttranscriptional Control of Peripheral Tissue Antigens in Medullary Thymic Epithelial Cells

Autoimmune regulator (Aire) is a transcriptional regulator of peripheral tissue antigens (PTAs) and microRNAs (miRNAs) in medullary thymic epithelial cells (mTECs). In this study, we tested the hypothesis that Aire also played a role as an upstream posttranscriptional controller in these cells and t...

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Detalles Bibliográficos
Autores principales:	Oliveira, Ernna H., Macedo, Claudia, Collares, Cristhianna V., Freitas, Ana Carolina, Donate, Paula Barbim, Sakamoto-Hojo, Elza T., Donadi, Eduardo A., Passos, Geraldo A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120147/ https://www.ncbi.nlm.nih.gov/pubmed/27933063 http://dx.doi.org/10.3389/fimmu.2016.00526

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