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DDIT4 regulates mesenchymal stem cell fate by mediating between HIF1α and mTOR signalling

Stem cell fate decisions to remain quiescent, self-renew or differentiate are largely governed by the interplay between extracellular signals from the niche and the cell intrinsic signal cascades and transcriptional programs. Here we demonstrate that DNA Damage Inducible Transcript 4 (DDIT4) acts as...

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Detalles Bibliográficos
Autores principales:	Gharibi, Borzo, Ghuman, Mandeep, Hughes, Francis J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120275/ https://www.ncbi.nlm.nih.gov/pubmed/27876894 http://dx.doi.org/10.1038/srep36889

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