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Non-stimulated adrenal venous sampling using Dyna computed tomography in patients with primary aldosteronism
In this retrospective study, we aimed to examine the effect of applying Dyna computed tomography (CT) on the success rate of adrenal venous sampling (AVS) without adrenocorticotropic hormone stimulation. A total of 100 consecutive patients with primary aldosteronism who underwent AVS between May 201...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120298/ https://www.ncbi.nlm.nih.gov/pubmed/27876824 http://dx.doi.org/10.1038/srep37143 |
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author | Chang, Chin-Chen Lee, Bo-Ching Liu, Kao-Lang Chang, Yeun-Chung Wu, Vin-Cent Huang, Kuo-How |
author_facet | Chang, Chin-Chen Lee, Bo-Ching Liu, Kao-Lang Chang, Yeun-Chung Wu, Vin-Cent Huang, Kuo-How |
author_sort | Chang, Chin-Chen |
collection | PubMed |
description | In this retrospective study, we aimed to examine the effect of applying Dyna computed tomography (CT) on the success rate of adrenal venous sampling (AVS) without adrenocorticotropic hormone stimulation. A total of 100 consecutive patients with primary aldosteronism who underwent AVS between May 2012 and July 2015 were enrolled. In all the cases, Dyna CT was used in AVS to validate catheter position in the right adrenal vein. A selectivity index (cortisol(adrenal vein) /cortisol(inferior vena cava)) of ≥2.0 of both adrenal veins were required for successful AVS. Dyna CT indicated misplaced catheters in 16 patients; of these patients, 75% (12/16) eventually had successful right AVS after catheter repositioning. The success rate of initial sampling at the right adrenal vein was 76% (76/100), which increased to 88% (88/100) after Dyna CT was applied (p < 0.001). The most common inadvertently catheterised vessels detected using Dyna CT were the accessory hepatic veins (56.3%, 9/16), followed by the renal capsular veins (37.5%, 6/16). The overall success rate of non-stimulated AVS using Dyna CT was 87% (87/100). Thus, the application of Dyna CT further increased the success rate of non-stimulated AVS. |
format | Online Article Text |
id | pubmed-5120298 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-51202982016-11-28 Non-stimulated adrenal venous sampling using Dyna computed tomography in patients with primary aldosteronism Chang, Chin-Chen Lee, Bo-Ching Liu, Kao-Lang Chang, Yeun-Chung Wu, Vin-Cent Huang, Kuo-How Sci Rep Article In this retrospective study, we aimed to examine the effect of applying Dyna computed tomography (CT) on the success rate of adrenal venous sampling (AVS) without adrenocorticotropic hormone stimulation. A total of 100 consecutive patients with primary aldosteronism who underwent AVS between May 2012 and July 2015 were enrolled. In all the cases, Dyna CT was used in AVS to validate catheter position in the right adrenal vein. A selectivity index (cortisol(adrenal vein) /cortisol(inferior vena cava)) of ≥2.0 of both adrenal veins were required for successful AVS. Dyna CT indicated misplaced catheters in 16 patients; of these patients, 75% (12/16) eventually had successful right AVS after catheter repositioning. The success rate of initial sampling at the right adrenal vein was 76% (76/100), which increased to 88% (88/100) after Dyna CT was applied (p < 0.001). The most common inadvertently catheterised vessels detected using Dyna CT were the accessory hepatic veins (56.3%, 9/16), followed by the renal capsular veins (37.5%, 6/16). The overall success rate of non-stimulated AVS using Dyna CT was 87% (87/100). Thus, the application of Dyna CT further increased the success rate of non-stimulated AVS. Nature Publishing Group 2016-11-23 /pmc/articles/PMC5120298/ /pubmed/27876824 http://dx.doi.org/10.1038/srep37143 Text en Copyright © 2016, The Author(s) http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
spellingShingle | Article Chang, Chin-Chen Lee, Bo-Ching Liu, Kao-Lang Chang, Yeun-Chung Wu, Vin-Cent Huang, Kuo-How Non-stimulated adrenal venous sampling using Dyna computed tomography in patients with primary aldosteronism |
title | Non-stimulated adrenal venous sampling using Dyna computed tomography in patients with primary aldosteronism |
title_full | Non-stimulated adrenal venous sampling using Dyna computed tomography in patients with primary aldosteronism |
title_fullStr | Non-stimulated adrenal venous sampling using Dyna computed tomography in patients with primary aldosteronism |
title_full_unstemmed | Non-stimulated adrenal venous sampling using Dyna computed tomography in patients with primary aldosteronism |
title_short | Non-stimulated adrenal venous sampling using Dyna computed tomography in patients with primary aldosteronism |
title_sort | non-stimulated adrenal venous sampling using dyna computed tomography in patients with primary aldosteronism |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120298/ https://www.ncbi.nlm.nih.gov/pubmed/27876824 http://dx.doi.org/10.1038/srep37143 |
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