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Genetic variations in the PI3K-PTEN-AKT-mTOR pathway are associated with distant metastasis in nasopharyngeal carcinoma patients treated with intensity-modulated radiation therapy

Distant metastasis is the primary failure pattern of nasopharyngeal carcinoma(NPC) in intensity-modulated radiation therapy(IMRT) era. This study was conducted to find the impact of genetic variations in the phosphatidylinositol 3-kinase(PI3K)/phosphatase and tensin homologue(PTEN)/v-akt murine thym...

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Detalles Bibliográficos
Autores principales:	Guo, Qiaojuan, Lu, Tianzhu, Chen, Yan, Su, Ying, Zheng, Yuhong, Chen, Zeng, Chen, Chao, Lin, Shaojun, Pan, Jianji, Yuan, Xianglin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120316/ https://www.ncbi.nlm.nih.gov/pubmed/27876891 http://dx.doi.org/10.1038/srep37576

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