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miR-706 inhibits the oxidative stress-induced activation of PKCα/TAOK1 in liver fibrogenesis

Oxidative stress induces the activation of liver fibrogenic cells (myofibroblasts), thus promoting the expression of fibrosis-related genes, leading to hepatic fibrogenesis. MicroRNAs (miRNAs) are a new class of small RNAs ~18–25 nucleotides in length involved in post-transcriptional regulation of g...

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Detalles Bibliográficos
Autores principales: Yin, Ruili, Guo, Duo, Zhang, Shuxian, Zhang, Xiuying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120320/
https://www.ncbi.nlm.nih.gov/pubmed/27876854
http://dx.doi.org/10.1038/srep37509