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mTORC1 is Required for Brown Adipose Tissue Recruitment and Metabolic Adaptation to Cold
In response to cold, brown adipose tissue (BAT) increases its metabolic rate and expands its mass to produce heat required for survival, a process known as BAT recruitment. The mechanistic target of rapamycin complex 1 (mTORC1) controls metabolism, cell growth and proliferation, but its role in regu...
Autores principales: | Labbé, Sébastien M., Mouchiroud, Mathilde, Caron, Alexandre, Secco, Blandine, Freinkman, Elizaveta, Lamoureux, Guillaume, Gélinas, Yves, Lecomte, Roger, Bossé, Yohan, Chimin, Patricia, Festuccia, William T., Richard, Denis, Laplante, Mathieu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120333/ https://www.ncbi.nlm.nih.gov/pubmed/27876792 http://dx.doi.org/10.1038/srep37223 |
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