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Deciphering fact from artifact when using reporter assays to investigate the roles of host factors on L1 retrotransposition
BACKGROUND: The Long INterspersed Element-1 (L1, LINE-1) is the only autonomous mobile DNA element in humans and has generated as much as half of the genome. Due to increasing clinical interest in the roles of L1 in cancer, embryogenesis and neuronal development, it has become a priority to understa...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120415/ https://www.ncbi.nlm.nih.gov/pubmed/27895722 http://dx.doi.org/10.1186/s13100-016-0079-3 |