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Nitric oxide has contrasting age-dependent effects on the functionality of murine hematopoietic stem cells
BACKGROUND: The success of hematopoietic stem cell (HSC) transplantation is dependent on the quality of the donor HSCs. Some sources of HSCs display reduced engraftment efficiency either because of inadequate number (e.g., fetal liver and cord blood), or age-related dysfunction (e.g. in older indivi...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120451/ https://www.ncbi.nlm.nih.gov/pubmed/27876094 http://dx.doi.org/10.1186/s13287-016-0433-x |