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A statistical model for the analysis of beta values in DNA methylation studies

BACKGROUND: The analysis of DNA methylation is a key component in the development of personalized treatment approaches. A common way to measure DNA methylation is the calculation of beta values, which are bounded variables of the form M/(M+U) that are generated by Illumina’s 450k BeadChip array. The...

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Detalles Bibliográficos
Autores principales:	Weinhold, Leonie, Wahl, Simone, Pechlivanis, Sonali, Hoffmann, Per, Schmid, Matthias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120494/ https://www.ncbi.nlm.nih.gov/pubmed/27875981 http://dx.doi.org/10.1186/s12859-016-1347-4

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