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Phase I study of low-dose metronomic temozolomide for recurrent malignant gliomas
BACKGROUND: The treatment goal for recurrent malignant gliomas centers on disease stabilization while minimizing therapy-related side effects. Metronomic dosing of cytotoxic chemotherapy has emerged as a promising option to achieve this objective. METHODS: This phase I study was performed using metr...
Autores principales: | Wong, Eric T., Timmons, Joshua, Callahan, Amy, O’Loughlin, Lauren, Giarusso, Bridget, Alsop, David C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120517/ https://www.ncbi.nlm.nih.gov/pubmed/27876012 http://dx.doi.org/10.1186/s12885-016-2945-2 |
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