Cargando…

Mendelian inheritance of trimodal CpG methylation sites suggests distal cis-acting genetic effects

BACKGROUND: Environmentally influenced phenotypes, such as obesity and insulin resistance, can be transmitted over multiple generations. Epigenetic modifications, such as methylation of DNA cytosine-guanine (CpG) pairs, may be carriers of inherited information. At the population level, the methylati...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zaghlool, Shaza B., Al-Shafai, Mashael, Al Muftah, Wadha A., Kumar, Pankaj, Gieger, Christian, Waldenberger, Melanie, Falchi, Mario, Suhre, Karsten
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120560/ https://www.ncbi.nlm.nih.gov/pubmed/27895808 http://dx.doi.org/10.1186/s13148-016-0295-1

Ejemplares similares

Association of DNA methylation with age, gender, and smoking in an Arab population
por: Zaghlool, Shaza B, et al.
Publicado: (2015)

PopPAnTe: population and pedigree association testing for quantitative data
por: Visconti, Alessia, et al.
Publicado: (2017)

Evaluation of SNP calling using single and multiple-sample calling algorithms by validation against array base genotyping and Mendelian inheritance
por: Kumar, Pankaj, et al.
Publicado: (2014)

Epigenetic associations of type 2 diabetes and BMI in an Arab population
por: Al Muftah, Wadha A., et al.
Publicado: (2016)

Deep molecular phenotypes link complex disorders and physiological insult to CpG methylation
por: Zaghlool, Shaza B, et al.
Publicado: (2018)

Revealing the role of the human blood plasma proteome in obesity using genetic drivers
por: Zaghlool, Shaza B., et al.
Publicado: (2021)

Epigenetic inheritance is unfaithful at intermediately methylated CpG sites
por: Hay, Amir D., et al.
Publicado: (2023)

The Special Features of Prenatal and Preimplantation Genetic Counseling in Arab Countries
por: Malik, Shaza D., et al.
Publicado: (2022)

Seven novel glucose-6-phosphate dehydrogenase (G6PD) deficiency variants identified in the Qatari population
por: Malik, Shaza, et al.
Publicado: (2021)

Inheritance of an Epigenetic Mark: The CpG DNA Methyltransferase 1 Is Required for De Novo Establishment of a Complex Pattern of Non-CpG Methylation
por: Grandjean, Valérie, et al.
Publicado: (2007)

Metabolic syndrome and the plasma proteome: from association to causation
por: Elhadad, Mohamed A., et al.
Publicado: (2021)

Role of CpG deserts in the epigenetic transgenerational inheritance of differential DNA methylation regions
por: Skinner, Michael K, et al.
Publicado: (2014)

Preservation of methylated CpG dinucleotides in human CpG islands
por: Panchin, Alexander Y., et al.
Publicado: (2016)

Collaboration between CpG sites is needed for stable somatic inheritance of DNA methylation states
por: Haerter, Jan O., et al.
Publicado: (2014)

Suppressive CpG
por: Van Epps, Heather L.
Publicado: (2005)

Factors to preserve CpG-rich sequences in methylated CpG islands
por: Miyahara, Hiroki, et al.
Publicado: (2015)

Matching Drug Metabolites from Non-Targeted Metabolomics to Self-Reported Medication in the Qatar Biobank Study
por: Suhre, Karsten, et al.
Publicado: (2022)

In Vivo Control of CpG and Non-CpG DNA Methylation by DNA Methyltransferases
por: Arand, Julia, et al.
Publicado: (2012)

CpG and Non-CpG Methylation in Epigenetic Gene Regulation and Brain Function
por: Jang, Hyun Sik, et al.
Publicado: (2017)

Deletion Hotspots in AMACR Promoter CpG Island Are cis-Regulatory Elements Controlling the Gene Expression in the Colon
por: Zhang, Xiang, et al.
Publicado: (2009)

Assessing non-Mendelian Inheritance in Inherited Axonopathies
por: Bis-Brewer, Dana M., et al.
Publicado: (2020)

Prediction of CpG-island function: CpG clustering vs. sliding-window methods
por: Hackenberg, Michael, et al.
Publicado: (2010)

CpG Methylation Altered the Stability and Structure of the i-Motifs Located in the CpG Islands
por: Oshikawa, Daiki, et al.
Publicado: (2022)

Mendelian Randomization Analysis Identifies CpG Sites as Putative Mediators for Genetic Influences on Cardiovascular Disease Risk
por: Richardson, Tom G., et al.
Publicado: (2017)

CMIC: predicting DNA methylation inheritance of CpG islands with embedding vectors of variable-length k-mers
por: Maruyama, Osamu, et al.
Publicado: (2022)

CpGIF: an algorithm for the identification of CpG islands
por: Sujuan, Ye, et al.
Publicado: (2008)

Epigenetics meets proteomics in an epigenome-wide association study with circulating blood plasma protein traits
por: Zaghlool, Shaza B., et al.
Publicado: (2020)

On the potential of models for location and scale for genome-wide DNA methylation data
por: Wahl, Simone, et al.
Publicado: (2014)

The Effects of O(6)-methyl Guanine DNA-methyl Transferase Promotor Methylation and CpG1, CpG2, CpG3 and CpG4 Methylation on Treatment Response and their Prognostic Significance in Patients with Glioblastoma
por: Yildiz, OG, et al.
Publicado: (2020)

The Control Region of Mitochondrial DNA Shows an Unusual CpG and Non-CpG Methylation Pattern
por: Bellizzi, Dina, et al.
Publicado: (2013)

Evaluation of single CpG sites as proxies of CpG island methylation states at the genome scale
por: Barrera, Víctor, et al.
Publicado: (2012)

Low biological fluctuation of mitochondrial CpG and non-CpG methylation at the single-molecule level
por: Goldsmith, Chloe, et al.
Publicado: (2021)

Mendelian Randomization Identifies CpG Methylation Sites With Mediation Effects for Genetic Influences on BMD in Peripheral Blood Monocytes
por: Yu, Fangtang, et al.
Publicado: (2020)

Maternal obesity alters methylation level of cytosine in CpG island for epigenetic inheritance in fetal umbilical cord blood
por: Ma, Zhuoyao, et al.
Publicado: (2022)

Bidding the CpG island goodbye
por: Greally, John M
Publicado: (2013)

CpG oligodeoxynucleotides as mucosal adjuvants
por: Iho, Sumiko, et al.
Publicado: (2015)

CpGPAP: CpG island predictor analysis platform
por: Chuang, Li-Yeh, et al.
Publicado: (2012)

CpG islands or CpG clusters: how to identify functional GC-rich regions in a genome?
por: Han, Leng, et al.
Publicado: (2009)

In silico identification of single nucleotide variations at CpG sites regulating CpG island existence and size
por: Shyamala, Nivas, et al.
Publicado: (2022)

Genome-wide identification of methylated CpG sites in nongenital cutaneous warts
por: AL-Eitan, Laith N., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_gum3k8qopqonanp3f5vt5crjqt