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Somatic mutations of isocitrate dehydrogenases 1 and 2 are prognostic and follow-up markers in patients with acute myeloid leukaemia with normal karyotype

BACKGROUND: Mutations in the isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) genes are frequent molecular lesions in acute myeloid leukaemia with normal karyotype (AML-NK). The effects of IDH mutations on clinical features and treatment outcome in AML-NK have been widely investigated, but only a fe...

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Detalles Bibliográficos
Autores principales: Virijevic, Marijana, Karan-Djurasevic, Teodora, Marjanovic, Irena, Tosic, Natasa, Mitrovic, Mirjana, Djunic, Irena, Colovic, Natasa, Vidovic, Ana, Suvajdzic-Vukovic, Nada, Tomin, Dragica, Pavlovic, Sonja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120579/
https://www.ncbi.nlm.nih.gov/pubmed/27904446
http://dx.doi.org/10.1515/raon-2016-0044