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Cervantes and Quijote protect heterochromatin from aberrant recombination and lead the way to the nuclear periphery

Repairing double-strand breaks (DSBs) is particularly challenging in heterochromatin, where the abundance of repeated sequences exacerbates the risk of ectopic recombination and chromosome rearrangements. In Drosophila cells, faithful homologous recombination (HR) repair of heterochromatic DSBs reli...

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Detalles Bibliográficos
Autores principales: Ryu, Taehyun, Bonner, Melissa R., Chiolo, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120599/
https://www.ncbi.nlm.nih.gov/pubmed/27673416
http://dx.doi.org/10.1080/19491034.2016.1239683