Ingenol Disoxate: A Novel 4-Isoxazolecarboxylate Ester of Ingenol with Improved Properties for Treatment of Actinic Keratosis and Other Non-Melanoma Skin Cancers

INTRODUCTION: Ingenol mebutate gel (Picato(®), LEO Pharma A/S) is approved for the field treatment of actinic keratosis and is characterized by high sustained clearance of actinic lesions. The inherent propensity of ingenol mebutate towards chemical rearrangement necessitates refrigeration of the fi...

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Detalles Bibliográficos
Autores principales: Bertelsen, Malene, Stahlhut, Martin, Grue-Sørensen, Gunnar, Liang, Xifu, Christensen, Gitte Bach, Skak, Kresten, Engell, Karen Margrethe, Högberg, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120626/
https://www.ncbi.nlm.nih.gov/pubmed/27503482
http://dx.doi.org/10.1007/s13555-016-0137-2

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