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Crystal structure of 4-[4-(eth­oxy­carbon­yl)piperazin-1-yl]benzoic acid

The asymmetric unit of the title compound, C(14)H(18)N(2)O(4), contains two independent mol­ecules (A and B) which have essentially the same conformation. The piperazine rings adopts chair conformations with the N atoms out of plane. The dihedral angles formed by the four approximately planar C atom...

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Detalles Bibliográficos
Autores principales: Faizi, Md. Serajul Haque, Ahmad, Musheer, Golenya, Irina A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120704/
https://www.ncbi.nlm.nih.gov/pubmed/27920914
http://dx.doi.org/10.1107/S2056989016012482
Descripción
Sumario:The asymmetric unit of the title compound, C(14)H(18)N(2)O(4), contains two independent mol­ecules (A and B) which have essentially the same conformation. The piperazine rings adopts chair conformations with the N atoms out of plane. The dihedral angles formed by the four approximately planar C atoms of the piperazine ring and the benzene ring is 30.8 (5)° in mol­ecule A and 30.6 (5)° in mol­ecule B. In the crystal, mol­ecules A and B are connected by a pair of O—H⋯O hydrogen bonds, forming a dimer with graph-set notation R (2) (2)(8). Weak C—H⋯O hydrogen bonds connect the dimers, forming zigzag chains along [001].