Crystal structures of ethyl {2-[4-(4-iso­propyl­phen­yl)thia­zol-2-yl]phen­yl}carbamate and ethyl {2-[4-(3-nitro­phen­yl)thia­zol-2-yl]phen­yl}carbamate

The title compounds, C(21)H(22)N(2)O(2)S (I) and C(18)H(15)N(3)O(4)S (II), are structural analogs of the alkaloid Thio­sporine B. Both mol­ecules adopt a near-planar V-shaped conformation, which is consolidated by intra­molecular N—H⋯N and C—H⋯O hydrogen bonds. The crystal structure of (I) consists...

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Detalles Bibliográficos
Autores principales: Sukhonosova, Elena V., Sokov, Sergey A., Ostapenko, Gennady I., Bunev, Alexander S., Dorovatovskii, Pavel V., Zubavichus, Yan V., Khrustalev, Victor N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2016
Materias:
Research Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120716/
https://www.ncbi.nlm.nih.gov/pubmed/27920926
http://dx.doi.org/10.1107/S2056989016013104
Descripción
Sumario:The title compounds, C(21)H(22)N(2)O(2)S (I) and C(18)H(15)N(3)O(4)S (II), are structural analogs of the alkaloid Thio­sporine B. Both mol­ecules adopt a near-planar V-shaped conformation, which is consolidated by intra­molecular N—H⋯N and C—H⋯O hydrogen bonds. The crystal structure of (I) consists of mlecular stacks along the a axis, in which the mol­ecules are linked to each other by π(S)⋯π(C) inter­actions. In the crystal of (II), mol­ecules are linked into chains by C—H⋯O hydrogen bonds and the chains are cross-linked into (100) sheets by π–π stacking inter­actions.

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