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In Vitro Apoptotic Effects of Farnesyltransferase blockade in Acute Myeloid Leukemia Cells

Farnesyltransferase inhibitors (FTIs) are a class of oral anti-cancer drugs currently tested in phase I-II clinical trials for treatment of hematological malignancies. The in vitro effects of various FTIs (alpha-hydroxyfarnesylphosphonic acid, manumycin-A and SCH66336) were tested on CD34(+) KG1a ce...

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Detalles Bibliográficos
Autores principales:	Giudice, V, Ricci, P, Marino, L, Rocco, M, Villani, G, Langella, M, Manente, L, Seneca, E, Ferrara, I, Pezzullo, L, Serio, B, Selleri, C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Università di Salerno 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120747/ https://www.ncbi.nlm.nih.gov/pubmed/27896224

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