Genome-wide association studies of autoimmune vitiligo identify 23 new risk loci and highlight key pathways and regulatory variants

Vitiligo is an autoimmune disease in which depigmented skin results from destruction of melanocytes(1), with epidemiologic association with other autoimmune diseases(2). In previous linkage and genome-wide association studies (GWAS1, GWAS2), we identified 27 vitiligo susceptibility loci in patients...

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Autores principales: Jin, Ying, Andersen, Genevieve, Yorgov, Daniel, Ferrara, Tracey M, Ben, Songtao, Brownson, Kelly M, Holland, Paulene J, Birlea, Stanca A, Siebert, Janet, Hartmann, Anke, Lienert, Anne, van Geel, Nanja, Lambert, Jo, Luiten, Rosalie M, Wolkerstorfer, Albert, van der Veen, JP Wietze, Bennett, Dorothy C, Taïeb, Alain, Ezzedine, Khaled, Kemp, E Helen, Gawkrodger, David J, Weetman, Anthony P, Kõks, Sulev, Prans, Ele, Kingo, Külli, Karelson, Maire, Wallace, Margaret R, McCormack, Wayne T, Overbeck, Andreas, Moretti, Silvia, Colucci, Roberta, Picardo, Mauro, Silverberg, Nanette B, Olsson, Mats, Valle, Yan, Korobko, Igor, Böhm, Markus, Lim, Henry W., Hamzavi, Iltefat, Zhou, Li, Mi, Qing-Sheng, Fain, Pamela R., Santorico, Stephanie A, Spritz, Richard A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120758/
https://www.ncbi.nlm.nih.gov/pubmed/27723757
http://dx.doi.org/10.1038/ng.3680

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