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Alternative BCG delivery strategies improve protection against Mycobacterium tuberculosis in non-human primates: Protection associated with mycobacterial antigen-specific CD4 effector memory T-cell populations

Intradermal (ID) BCG injection provides incomplete protection against TB in humans and experimental models. Alternative BCG vaccination strategies may improve protection in model species, including rhesus macaques. This study compares the immunogenicity and efficacy of BCG administered by ID and int...

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Detalles Bibliográficos
Autores principales:	Sharpe, S., White, A., Sarfas, C., Sibley, L., Gleeson, F., McIntyre, A., Basaraba, R., Clark, S., Hall, G., Rayner, E., Williams, A., Marsh, P.D., Dennis, M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Churchill Livingstone 2016
Materias:	Model Systems
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120991/ https://www.ncbi.nlm.nih.gov/pubmed/27865390 http://dx.doi.org/10.1016/j.tube.2016.09.004

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