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Necrotizing tracheobronchitis associated with rheumatoid arthritis

We report a case of necrotizing tracheobronchitis with rheumatoid arthritis. A 64 year-old-man presented with dry cough and was initially diagnosed with community-acquired pneumonia. The patient was admitted; he received initial antibiotic treatment. The treatment was effective and the symptoms wors...

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Detalles Bibliográficos
Autores principales: Kajikawa, Shigehisa, Noda, Kazushi, Nozaki, Yasuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121158/
https://www.ncbi.nlm.nih.gov/pubmed/27896063
http://dx.doi.org/10.1016/j.rmcr.2016.11.006
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author Kajikawa, Shigehisa
Noda, Kazushi
Nozaki, Yasuhiro
author_facet Kajikawa, Shigehisa
Noda, Kazushi
Nozaki, Yasuhiro
author_sort Kajikawa, Shigehisa
collection PubMed
description We report a case of necrotizing tracheobronchitis with rheumatoid arthritis. A 64 year-old-man presented with dry cough and was initially diagnosed with community-acquired pneumonia. The patient was admitted; he received initial antibiotic treatment. The treatment was effective and the symptoms worsened. Bronchoscopy was performed for more thorough examination. It showed that white and soft tissues were on the trachea-bronchus. Transbronchial biopsy of the tracheal lesions revealed necrotic tissue with squamous metaplasia and inflammatory cells. Whereas, symmetrical arthralgia of multiple joints of the limbs was noted and rheumatoid factor and anti-cyclic citrullinated peptide antibody of levels were high. According to these results, the patient was diagnosed with rheumatoid arthritis. In this case, necrotizing tracheobronchitis occurred as a result of systemic inflammation associated with rheumatoid arthritis. An acute exacerbation of the patient's respiratory condition was treated with steroid therapy. Tracheal findings and respiratory symptoms were improved by steroid therapy.
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spelling pubmed-51211582016-11-28 Necrotizing tracheobronchitis associated with rheumatoid arthritis Kajikawa, Shigehisa Noda, Kazushi Nozaki, Yasuhiro Respir Med Case Rep Article We report a case of necrotizing tracheobronchitis with rheumatoid arthritis. A 64 year-old-man presented with dry cough and was initially diagnosed with community-acquired pneumonia. The patient was admitted; he received initial antibiotic treatment. The treatment was effective and the symptoms worsened. Bronchoscopy was performed for more thorough examination. It showed that white and soft tissues were on the trachea-bronchus. Transbronchial biopsy of the tracheal lesions revealed necrotic tissue with squamous metaplasia and inflammatory cells. Whereas, symmetrical arthralgia of multiple joints of the limbs was noted and rheumatoid factor and anti-cyclic citrullinated peptide antibody of levels were high. According to these results, the patient was diagnosed with rheumatoid arthritis. In this case, necrotizing tracheobronchitis occurred as a result of systemic inflammation associated with rheumatoid arthritis. An acute exacerbation of the patient's respiratory condition was treated with steroid therapy. Tracheal findings and respiratory symptoms were improved by steroid therapy. Elsevier 2016-11-09 /pmc/articles/PMC5121158/ /pubmed/27896063 http://dx.doi.org/10.1016/j.rmcr.2016.11.006 Text en © 2016 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Kajikawa, Shigehisa
Noda, Kazushi
Nozaki, Yasuhiro
Necrotizing tracheobronchitis associated with rheumatoid arthritis
title Necrotizing tracheobronchitis associated with rheumatoid arthritis
title_full Necrotizing tracheobronchitis associated with rheumatoid arthritis
title_fullStr Necrotizing tracheobronchitis associated with rheumatoid arthritis
title_full_unstemmed Necrotizing tracheobronchitis associated with rheumatoid arthritis
title_short Necrotizing tracheobronchitis associated with rheumatoid arthritis
title_sort necrotizing tracheobronchitis associated with rheumatoid arthritis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121158/
https://www.ncbi.nlm.nih.gov/pubmed/27896063
http://dx.doi.org/10.1016/j.rmcr.2016.11.006
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