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Mast Cell Clonal Disorders: Classification, Diagnosis and Management
Mast cell clonal disorders are characterized by the clonal proliferation of pathological mast cells as a result of somatic mutations in the KIT gene, most commonly the D816V mutation. Accumulation and degranulation of these cells causes a wide variety of symptoms. Mast cell clonal disorders can be d...
Autores principales: | Onnes, Merel C., Tanno, Luciana K., Elberink, Joanne N. G. Oude |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121168/ https://www.ncbi.nlm.nih.gov/pubmed/27942432 http://dx.doi.org/10.1007/s40521-016-0103-3 |
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