The reproducibility of biomedical research: Sleepers awake!

There is increasing concern about the reliability of biomedical research, with recent articles suggesting that up to 85% of research funding is wasted. This article argues that an important reason for this is the inappropriate use of molecular techniques, particularly in the field of RNA biomarkers,...

Descripción completa

Detalles Bibliográficos
Autor principal: Bustin, Stephen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121206/
https://www.ncbi.nlm.nih.gov/pubmed/27896142
http://dx.doi.org/10.1016/j.bdq.2015.01.002
_version_ 1782469361668194304
author Bustin, Stephen A.
author_facet Bustin, Stephen A.
author_sort Bustin, Stephen A.
collection PubMed
description There is increasing concern about the reliability of biomedical research, with recent articles suggesting that up to 85% of research funding is wasted. This article argues that an important reason for this is the inappropriate use of molecular techniques, particularly in the field of RNA biomarkers, coupled with a tendency to exaggerate the importance of research findings.
format Online
Article
Text
id pubmed-5121206
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-51212062016-11-28 The reproducibility of biomedical research: Sleepers awake! Bustin, Stephen A. Biomol Detect Quantif Review Article There is increasing concern about the reliability of biomedical research, with recent articles suggesting that up to 85% of research funding is wasted. This article argues that an important reason for this is the inappropriate use of molecular techniques, particularly in the field of RNA biomarkers, coupled with a tendency to exaggerate the importance of research findings. Elsevier 2015-01-21 /pmc/articles/PMC5121206/ /pubmed/27896142 http://dx.doi.org/10.1016/j.bdq.2015.01.002 Text en © 2015 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review Article
Bustin, Stephen A.
The reproducibility of biomedical research: Sleepers awake!
title The reproducibility of biomedical research: Sleepers awake!
title_full The reproducibility of biomedical research: Sleepers awake!
title_fullStr The reproducibility of biomedical research: Sleepers awake!
title_full_unstemmed The reproducibility of biomedical research: Sleepers awake!
title_short The reproducibility of biomedical research: Sleepers awake!
title_sort reproducibility of biomedical research: sleepers awake!
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121206/
https://www.ncbi.nlm.nih.gov/pubmed/27896142
http://dx.doi.org/10.1016/j.bdq.2015.01.002
work_keys_str_mv AT bustinstephena thereproducibilityofbiomedicalresearchsleepersawake
AT bustinstephena reproducibilityofbiomedicalresearchsleepersawake

Ejemplares similares