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Signatures of natural selection on genetic variants affecting complex human traits()
It has recently been hypothesized that polygenic adaptation, resulting in modest allele frequency changes at many loci, could be a major mechanism behind the adaptation of complex phenotypes in human populations. Here we leverage the large number of variants that have been identified through genome-...
Autores principales: | Zhang, Ge, Muglia, Louis J., Chakraborty, Ranajit, Akey, Joshua M., Williams, Scott M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121263/ https://www.ncbi.nlm.nih.gov/pubmed/27896059 http://dx.doi.org/10.1016/j.atg.2013.10.002 |
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