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Increased Brain Neurotensin and NTSR2 Lead to Weak Nociception in NTSR3/Sortilin Knockout Mice

The neuropeptide neurotensin (NT) elicits numerous pharmacological effects through three different receptors (NTSR1, NTSR2, and NTSR3 also called sortilin). Pharmacological approaches and generation of NTSR1 and NTSR2-deficient mice allowed to determine the NT-induced antipsychotic like behavior, th...

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Detalles Bibliográficos
Autores principales: Devader, Christelle, Moreno, Sébastien, Roulot, Morgane, Deval, Emmanuel, Dix, Thomas, Morales, Carlos R., Mazella, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121284/
https://www.ncbi.nlm.nih.gov/pubmed/27932946
http://dx.doi.org/10.3389/fnins.2016.00542

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