A systems study reveals concurrent activation of AMPK and mTOR by amino acids

Amino acids (aa) are not only building blocks for proteins, but also signalling molecules, with the mammalian target of rapamycin complex 1 (mTORC1) acting as a key mediator. However, little is known about whether aa, independently of mTORC1, activate other kinases of the mTOR signalling network. To...

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Detalles Bibliográficos
Autores principales: Pezze, Piero Dalle, Ruf, Stefanie, Sonntag, Annika G., Langelaar-Makkinje, Miriam, Hall, Philip, Heberle, Alexander M., Navas, Patricia Razquin, van Eunen, Karen, Tölle, Regine C., Schwarz, Jennifer J., Wiese, Heike, Warscheid, Bettina, Deitersen, Jana, Stork, Björn, Fäßler, Erik, Schäuble, Sascha, Hahn, Udo, Horvatovich, Peter, Shanley, Daryl P., Thedieck, Kathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121333/
https://www.ncbi.nlm.nih.gov/pubmed/27869123
http://dx.doi.org/10.1038/ncomms13254

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