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Development of catecholamine and cortisol stress responses in zebrafish()()

Both adrenal catecholamines and steroids are known to be involved in the stress response, immune function, blood pressure and energy homeostasis. The response to stress is characterized by the activation of the hypothalamus–pituitary–adrenal (HPA) axis and the sympathetic-adrenomedullary system, tho...

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Autores principales: Eto, Kaoru, Mazilu-Brown, Jaime K., Henderson-MacLennan, Nicole, Dipple, Katrina M., McCabe, Edward R.B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121345/
https://www.ncbi.nlm.nih.gov/pubmed/27896111
http://dx.doi.org/10.1016/j.ymgmr.2014.08.003
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author Eto, Kaoru
Mazilu-Brown, Jaime K.
Henderson-MacLennan, Nicole
Dipple, Katrina M.
McCabe, Edward R.B.
author_facet Eto, Kaoru
Mazilu-Brown, Jaime K.
Henderson-MacLennan, Nicole
Dipple, Katrina M.
McCabe, Edward R.B.
author_sort Eto, Kaoru
collection PubMed
description Both adrenal catecholamines and steroids are known to be involved in the stress response, immune function, blood pressure and energy homeostasis. The response to stress is characterized by the activation of the hypothalamus–pituitary–adrenal (HPA) axis and the sympathetic-adrenomedullary system, though the correlation with activation and development is not well understood. We evaluated the stress response of both cortisol and catecholamines during development in zebrafish. Zebrafish at two different stages of development were stressed in one of two different ways and cortisol and catecholamine were measured. Cortisol was measured by enzyme immune assay and catecholamine was measured by ELISA. Our results show that stress responses are delayed until after the synthesis of both cortisol and catecholamines. These observations suggest that the development of HPA axis may be required for the acquisition of the stress response for cortisol and catecholamines.
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spelling pubmed-51213452016-11-28 Development of catecholamine and cortisol stress responses in zebrafish()() Eto, Kaoru Mazilu-Brown, Jaime K. Henderson-MacLennan, Nicole Dipple, Katrina M. McCabe, Edward R.B. Mol Genet Metab Rep Short Communication Both adrenal catecholamines and steroids are known to be involved in the stress response, immune function, blood pressure and energy homeostasis. The response to stress is characterized by the activation of the hypothalamus–pituitary–adrenal (HPA) axis and the sympathetic-adrenomedullary system, though the correlation with activation and development is not well understood. We evaluated the stress response of both cortisol and catecholamines during development in zebrafish. Zebrafish at two different stages of development were stressed in one of two different ways and cortisol and catecholamine were measured. Cortisol was measured by enzyme immune assay and catecholamine was measured by ELISA. Our results show that stress responses are delayed until after the synthesis of both cortisol and catecholamines. These observations suggest that the development of HPA axis may be required for the acquisition of the stress response for cortisol and catecholamines. Elsevier 2014-09-07 /pmc/articles/PMC5121345/ /pubmed/27896111 http://dx.doi.org/10.1016/j.ymgmr.2014.08.003 Text en © 2014 The Authors http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).
spellingShingle Short Communication
Eto, Kaoru
Mazilu-Brown, Jaime K.
Henderson-MacLennan, Nicole
Dipple, Katrina M.
McCabe, Edward R.B.
Development of catecholamine and cortisol stress responses in zebrafish()()
title Development of catecholamine and cortisol stress responses in zebrafish()()
title_full Development of catecholamine and cortisol stress responses in zebrafish()()
title_fullStr Development of catecholamine and cortisol stress responses in zebrafish()()
title_full_unstemmed Development of catecholamine and cortisol stress responses in zebrafish()()
title_short Development of catecholamine and cortisol stress responses in zebrafish()()
title_sort development of catecholamine and cortisol stress responses in zebrafish()()
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121345/
https://www.ncbi.nlm.nih.gov/pubmed/27896111
http://dx.doi.org/10.1016/j.ymgmr.2014.08.003
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