Can APOE and MTHFR polymorphisms have an influence on the severity of cardiovascular manifestations in Italian Pseudoxanthoma elasticum affected patients?

BACKGROUND: The clinical phenotype of Pseudoxanthoma elasticum (PXE) affected patients, although progressive with age, is very heterogeneous, even in the presence of identical ABCC6 mutations, thus suggesting the occurrence of modifier genes. Beside typical skin manifestations, the cardiovascular (C...

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Detalles Bibliográficos
Autores principales: Boraldi, Federica, Costa, Sonia, Rabacchi, Claudio, Ciani, Miriam, Vanakker, Olivier, Quaglino, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121367/
https://www.ncbi.nlm.nih.gov/pubmed/27896127
http://dx.doi.org/10.1016/j.ymgmr.2014.11.002

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