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Spontaneous formation of structurally diverse membrane channel architectures from a single antimicrobial peptide
Many antimicrobial peptides (AMPs) selectively target and form pores in microbial membranes. However, the mechanisms of membrane targeting, pore formation and function remain elusive. Here we report an experimentally guided unbiased simulation methodology that yields the mechanism of spontaneous por...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121426/ https://www.ncbi.nlm.nih.gov/pubmed/27874004 http://dx.doi.org/10.1038/ncomms13535 |