Epidermal Growth Factor Receptor Silencing Blunts the Slow Force Response to Myocardial Stretch

BACKGROUND: Myocardial stretch increases force biphasically: the Frank‐Starling mechanism followed by the slow force response (SFR). Based on pharmacological strategies, we proposed that epidermal growth factor (EGF) receptor (EGFR or ErbB1) activation is crucial for SFR development. Pharmacological...

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Detalles Bibliográficos
Autores principales: Brea, María S., Díaz, Romina G., Escudero, Daiana S., Caldiz, Claudia I., Portiansky, Enrique L., Morgan, Patricio E., Pérez, Néstor G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121502/
https://www.ncbi.nlm.nih.gov/pubmed/27744404
http://dx.doi.org/10.1161/JAHA.116.004017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121502/
https://www.ncbi.nlm.nih.gov/pubmed/27744404
http://dx.doi.org/10.1161/JAHA.116.004017

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