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Epidermal Growth Factor Receptor Silencing Blunts the Slow Force Response to Myocardial Stretch
BACKGROUND: Myocardial stretch increases force biphasically: the Frank‐Starling mechanism followed by the slow force response (SFR). Based on pharmacological strategies, we proposed that epidermal growth factor (EGF) receptor (EGFR or ErbB1) activation is crucial for SFR development. Pharmacological...
Autores principales: | Brea, María S., Díaz, Romina G., Escudero, Daiana S., Caldiz, Claudia I., Portiansky, Enrique L., Morgan, Patricio E., Pérez, Néstor G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121502/ https://www.ncbi.nlm.nih.gov/pubmed/27744404 http://dx.doi.org/10.1161/JAHA.116.004017 |
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