Cargando…

Protective Effect of Edaravone on Glutamate-Induced Neurotoxicity in Spiral Ganglion Neurons

Glutamate is an important excitatory neurotransmitter in mammalian brains, but excessive amount of glutamate can cause “excitotoxicity” and lead to neuronal death. As bipolar neurons, spiral ganglion neurons (SGNs) function as a “bridge” in transmitting auditory information from the ear to the brain...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bai, Xiaohui, Zhang, Chi, Chen, Aiping, Liu, Wenwen, Li, Jianfeng, Sun, Qian, Wang, Haibo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121579/ https://www.ncbi.nlm.nih.gov/pubmed/27957345 http://dx.doi.org/10.1155/2016/4034218

Ejemplares similares

Paeoniflorin protects spiral ganglion neurons from cisplatin‐induced ototoxicity: Possible relation to PINK1/BAD pathway
por: Yu, Xiaoyu, et al.
Publicado: (2019)

The Three-Dimensional Culture System with Matrigel and Neurotrophic Factors Preserves the Structure and Function of Spiral Ganglion Neuron In Vitro
por: Sun, Gaoying, et al.
Publicado: (2016)

Wnt Signaling Protects against Paclitaxel-Induced Spiral Ganglion Neuron Damage in the Mouse Cochlea In Vitro
por: Wang, Xue, et al.
Publicado: (2019)

Apoptosis-inducing factor and calpain upregulation in glutamate-induced injury of rat spiral ganglion neurons
por: DING, ZHONG-JIA, et al.
Publicado: (2015)

Spag6 Mutant Mice Have Defects in Development and Function of Spiral Ganglion Neurons, Apoptosis, and Higher Sensitivity to Paclitaxel
por: Li, Xiaofei, et al.
Publicado: (2017)

Protective Effect of Edaravone on Cyclophosphamide Induced Oxidative Stress and Neurotoxicity in Rats
por: Singh, Sanjiv, et al.
Publicado: (2019)

PRDX1 activates autophagy via the PTEN-AKT signaling pathway to protect against cisplatin-induced spiral ganglion neuron damage
por: Liu, Wenwen, et al.
Publicado: (2021)

Regulation of Spiral Ganglion Neuron Regeneration as a Therapeutic Strategy in Sensorineural Hearing Loss
por: Wang, Man, et al.
Publicado: (2022)

Glutathione Peroxidase 1 Protects Against Peroxynitrite-Induced Spiral Ganglion Neuron Damage Through Attenuating NF-κB Pathway Activation
por: Wang, Xue, et al.
Publicado: (2022)

In vitro neuroprotective effects of ciliary neurotrophic factor on dorsal root ganglion neurons with glutamate-induced neurotoxicity
por: Wen, Shu-yun, et al.
Publicado: (2017)

Inhibitory Effects of Edaravone in β-Amyloid-Induced Neurotoxicity in Rats
por: He, Feng, et al.
Publicado: (2014)

Mechanism and Prevention of Spiral Ganglion Neuron Degeneration in the Cochlea
por: Zhang, Li, et al.
Publicado: (2022)

Calpain Inhibitor PD150606 Attenuates Glutamate Induced Spiral Ganglion Neuron Apoptosis through Apoptosis Inducing Factor Pathway In Vitro
por: Ding, Zhong-Jia, et al.
Publicado: (2015)

Similarities in the Biophysical Properties of Spiral-Ganglion and Vestibular-Ganglion Neurons in Neonatal Rats
por: Kalluri, Radha
Publicado: (2021)

Considering the protective effect of exendin-4 against oxidative stress in spiral ganglion neurons
por: Wu, Hongxia, et al.
Publicado: (2023)

The Protective Effect of Edaravone on TDP-43 Plus Oxidative Stress-Induced Neurotoxicity in Neuronal Cells: Analysis of Its Neuroprotective Mechanisms Using RNA Sequencing
por: Soejima-Kusunoki, Aki, et al.
Publicado: (2022)

Astaxanthin Protects PC12 Cells against Homocysteine- and Glutamate-Induced Neurotoxicity
por: Chang, Chi-Huang, et al.
Publicado: (2020)

Ouabain-Induced Apoptosis in Cochlear Hair Cells and Spiral Ganglion Neurons In Vitro
por: Fu, Yong, et al.
Publicado: (2013)

Generation of a Spiral Ganglion Neuron Degeneration Mouse Model
por: Hu, Zhengqing, et al.
Publicado: (2021)

Protective effect of adenovirus-mediated erythropoietin expression on the spiral ganglion neurons in the rat inner ear
por: Zhong, Cheng, et al.
Publicado: (2018)

Potentiation of Brain-Derived Neurotrophic Factor-Induced Protection of Spiral Ganglion Neurons by C3 Exoenzyme/Rho Inhibitor
por: Harre, Jennifer, et al.
Publicado: (2021)

AIF knockdown induce apoptosis and mitochondrial dysfunction in cochlear spiral ganglion neurons in vitro
por: Zong, Liang, et al.
Publicado: (2020)

Spiral Ganglion Neuron Explant Culture and Electrophysiology on Multi Electrode Arrays
por: Hahnewald, Stefan, et al.
Publicado: (2016)

Spiral Ganglion Stem Cells Can Be Propagated and Differentiated Into Neurons and Glia
por: Diensthuber, Marc, et al.
Publicado: (2014)

Comprehensive transcriptome analysis of cochlear spiral ganglion neurons at multiple ages
por: Li, Chao, et al.
Publicado: (2020)

Developmental Changes in Peripherin-eGFP Expression in Spiral Ganglion Neurons
por: Elliott, Karen L., et al.
Publicado: (2021)

Pericytes control vascular stability and auditory spiral ganglion neuron survival
por: Zhang, Yunpei, et al.
Publicado: (2023)

Specification of neuronal subtypes in the spiral ganglion begins prior to birth in the mouse
por: Sanders, Tessa R., et al.
Publicado: (2022)

486 Molecular Mechanisms of Type II Spiral Ganglion Neuron Development
por: George, Deborah Jane, et al.
Publicado: (2023)

Brimonidine is neuroprotective against glutamate-induced neurotoxicity, oxidative stress, and hypoxia in purified rat retinal ganglion cells
por: Lee, Kelvin Yoon Chiang, et al.
Publicado: (2010)

Potential protective roles of phytochemicals on glutamate-induced neurotoxicity: A review
por: Afshari, Amir R., et al.
Publicado: (2020)

Endoplasmic reticulum stress is involved in spiral ganglion neuron apoptosis following chronic kanamycin-induced deafness
por: Tu, Yaqin, et al.
Publicado: (2019)

Corrigendum: Potentiation of brain-derived neurotrophic factor-induced protection of spiral ganglion neurons by C3 exoenzyme/Rho inhibitor
por: Harre, Jennifer, et al.
Publicado: (2022)

Protective Effect of Edaravone in Primary Cerebellar Granule Neurons against Iodoacetic Acid-Induced Cell Injury
por: Zhou, Xinhua, et al.
Publicado: (2015)

In vitro Methods to Cultivate Spiral Ganglion Cells, and Purification of Cellular Subtypes for Induced Neuronal Reprogramming
por: Meas, Steven J., et al.
Publicado: (2018)

Purification of Fibroblasts From the Spiral Ganglion
por: Anacker, Annett, et al.
Publicado: (2022)

Chronic cigarette smoke exposure drives spiral ganglion neuron loss in mice
por: Paquette, Stephen T., et al.
Publicado: (2018)

Macrophage depletion attenuates degeneration of spiral ganglion neurons in kanamycin-induced unilateral hearing loss model
por: Shimada, Mari Dias, et al.
Publicado: (2023)

Neuronal Survival, Morphology and Outgrowth of Spiral Ganglion Neurons Using a Defined Growth Factor Combination
por: Schwieger, Jana, et al.
Publicado: (2015)

Parkin overexpression protects retinal ganglion cells against glutamate excitotoxicity
por: Hu, Xinxin, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_j3mi4f1tlei3qmnl62vooojv12