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Structural and functional probing of PorZ, an essential bacterial surface component of the type-IX secretion system of human oral-microbiomic Porphyromonas gingivalis.
Porphyromonas gingivalis is a member of the human oral microbiome abundant in dysbiosis and implicated in the pathogenesis of periodontal (gum) disease. It employs a newly described type-IX secretion system (T9SS) for secretion of virulence factors. Cargo proteins destined for secretion through T9SS...
Autores principales: | Lasica, Anna M., Goulas, Theodoros, Mizgalska, Danuta, Zhou, Xiaoyan, de Diego, Iñaki, Ksiazek, Mirosław, Madej, Mariusz, Guo, Yonghua, Guevara, Tibisay, Nowak, Magdalena, Potempa, Barbara, Goel, Apoorv, Sztukowska, Maryta, Prabhakar, Apurva T., Bzowska, Monika, Widziolek, Magdalena, Thøgersen, Ida B., Enghild, Jan J., Simonian, Mary, Kulczyk, Arkadiusz W., Nguyen, Ky-Anh, Potempa, Jan, Gomis-Rüth, F. Xavier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121618/ https://www.ncbi.nlm.nih.gov/pubmed/27883039 http://dx.doi.org/10.1038/srep37708 |
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