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17-oxo-DHA displays additive anti-inflammatory effects with fluticasone propionate and inhibits the NLRP3 inflammasome

Chronic obstructive pulmonary disease (COPD) is characterized by reduced lung function associated with increased local and systemic inflammatory markers, such as TNFα and IL-1β. Glucocorticoids are used to treat this chronic disease, however their efficacy is low and new drugs are very much required...

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Detalles Bibliográficos
Autores principales: Cipollina, Chiara, Di Vincenzo, Serena, Siena, Liboria, Di Sano, Caterina, Gjomarkaj, Mark, Pace, Elisabetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121625/
https://www.ncbi.nlm.nih.gov/pubmed/27883019
http://dx.doi.org/10.1038/srep37625