The Warburg Effect Mediator Pyruvate Kinase M2 Expression and Regulation in the Retina

The tumor form of pyruvate kinase M2 (PKM2) undergoes tyrosine phosphorylation and gives rise to the Warburg effect. The Warburg effect defines a pro-oncogenic metabolism switch such that cancer cells take up more glucose than normal tissue and favor incomplete oxidation of glucose, even in the pres...

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Detalles Bibliográficos
Autores principales: Rajala, Raju V. S., Rajala, Ammaji, Kooker, Christopher, Wang, Yuhong, Anderson, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121888/
https://www.ncbi.nlm.nih.gov/pubmed/27883057
http://dx.doi.org/10.1038/srep37727

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121888/
https://www.ncbi.nlm.nih.gov/pubmed/27883057
http://dx.doi.org/10.1038/srep37727

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