Hemophagocytic lymphohistiocytosis complicating a T-cell rich B-cell lymphoma

BACKGROUND: Hemophagocytic lymphohistiocytosis in adults is often secundary to an infection or a neoplasm. In this last case, T cell lymphomas are the most frequent causes. Hemophagocytic lymphohistiocytosis secundary to a B cell lymphoma has been rarely reported. CASE PRESENTATION: We describe a ca...

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Detalles Bibliográficos
Autores principales: Mahtat, El Mehdi, Zine, Maryem, Allaoui, Mohamed, Kerbout, Malika, Messaoudi, Nezha, Doghmi, Kamal, Mikdame, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122011/
https://www.ncbi.nlm.nih.gov/pubmed/27904750
http://dx.doi.org/10.1186/s12878-016-0065-5
Descripción
Sumario:BACKGROUND: Hemophagocytic lymphohistiocytosis in adults is often secundary to an infection or a neoplasm. In this last case, T cell lymphomas are the most frequent causes. Hemophagocytic lymphohistiocytosis secundary to a B cell lymphoma has been rarely reported. CASE PRESENTATION: We describe a case of a hemophagocytic lymphohistiocytosis complicating a T-cell rich B-cell lymphoma treated with conventionnal chemotherapy leading to a complete remission. CONCLUSION: Prompt etiologic diagnosis and treatment of hemophagocytic lymphohistiocytosis leads to satisfactory outcome.

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