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Hemophagocytic lymphohistiocytosis complicating a T-cell rich B-cell lymphoma

BACKGROUND: Hemophagocytic lymphohistiocytosis in adults is often secundary to an infection or a neoplasm. In this last case, T cell lymphomas are the most frequent causes. Hemophagocytic lymphohistiocytosis secundary to a B cell lymphoma has been rarely reported. CASE PRESENTATION: We describe a ca...

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Autores principales: Mahtat, El Mehdi, Zine, Maryem, Allaoui, Mohamed, Kerbout, Malika, Messaoudi, Nezha, Doghmi, Kamal, Mikdame, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122011/
https://www.ncbi.nlm.nih.gov/pubmed/27904750
http://dx.doi.org/10.1186/s12878-016-0065-5
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author Mahtat, El Mehdi
Zine, Maryem
Allaoui, Mohamed
Kerbout, Malika
Messaoudi, Nezha
Doghmi, Kamal
Mikdame, Mohamed
author_facet Mahtat, El Mehdi
Zine, Maryem
Allaoui, Mohamed
Kerbout, Malika
Messaoudi, Nezha
Doghmi, Kamal
Mikdame, Mohamed
author_sort Mahtat, El Mehdi
collection PubMed
description BACKGROUND: Hemophagocytic lymphohistiocytosis in adults is often secundary to an infection or a neoplasm. In this last case, T cell lymphomas are the most frequent causes. Hemophagocytic lymphohistiocytosis secundary to a B cell lymphoma has been rarely reported. CASE PRESENTATION: We describe a case of a hemophagocytic lymphohistiocytosis complicating a T-cell rich B-cell lymphoma treated with conventionnal chemotherapy leading to a complete remission. CONCLUSION: Prompt etiologic diagnosis and treatment of hemophagocytic lymphohistiocytosis leads to satisfactory outcome.
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spelling pubmed-51220112016-11-30 Hemophagocytic lymphohistiocytosis complicating a T-cell rich B-cell lymphoma Mahtat, El Mehdi Zine, Maryem Allaoui, Mohamed Kerbout, Malika Messaoudi, Nezha Doghmi, Kamal Mikdame, Mohamed BMC Hematol Case Report BACKGROUND: Hemophagocytic lymphohistiocytosis in adults is often secundary to an infection or a neoplasm. In this last case, T cell lymphomas are the most frequent causes. Hemophagocytic lymphohistiocytosis secundary to a B cell lymphoma has been rarely reported. CASE PRESENTATION: We describe a case of a hemophagocytic lymphohistiocytosis complicating a T-cell rich B-cell lymphoma treated with conventionnal chemotherapy leading to a complete remission. CONCLUSION: Prompt etiologic diagnosis and treatment of hemophagocytic lymphohistiocytosis leads to satisfactory outcome. BioMed Central 2016-11-24 /pmc/articles/PMC5122011/ /pubmed/27904750 http://dx.doi.org/10.1186/s12878-016-0065-5 Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Mahtat, El Mehdi
Zine, Maryem
Allaoui, Mohamed
Kerbout, Malika
Messaoudi, Nezha
Doghmi, Kamal
Mikdame, Mohamed
Hemophagocytic lymphohistiocytosis complicating a T-cell rich B-cell lymphoma
title Hemophagocytic lymphohistiocytosis complicating a T-cell rich B-cell lymphoma
title_full Hemophagocytic lymphohistiocytosis complicating a T-cell rich B-cell lymphoma
title_fullStr Hemophagocytic lymphohistiocytosis complicating a T-cell rich B-cell lymphoma
title_full_unstemmed Hemophagocytic lymphohistiocytosis complicating a T-cell rich B-cell lymphoma
title_short Hemophagocytic lymphohistiocytosis complicating a T-cell rich B-cell lymphoma
title_sort hemophagocytic lymphohistiocytosis complicating a t-cell rich b-cell lymphoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122011/
https://www.ncbi.nlm.nih.gov/pubmed/27904750
http://dx.doi.org/10.1186/s12878-016-0065-5
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