Role of cytochrome c in α-synuclein radical formation: implications of α-synuclein in neuronal death in Maneb- and paraquat-induced model of Parkinson’s disease

BACKGROUND: The pathological features of Parkinson’s disease (PD) include an abnormal accumulation of α-synuclein in the surviving dopaminergic neurons. Though PD is multifactorial, several epidemiological reports show an increased incidence of PD with co-exposure to pesticides such as Maneb and par...

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Detalles Bibliográficos
Autores principales: Kumar, Ashutosh, Ganini, Douglas, Mason, Ronald P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122029/
https://www.ncbi.nlm.nih.gov/pubmed/27884192
http://dx.doi.org/10.1186/s13024-016-0135-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122029/
https://www.ncbi.nlm.nih.gov/pubmed/27884192
http://dx.doi.org/10.1186/s13024-016-0135-y

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