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Abnormal primary and permanent dentitions with ectodermal symptoms predict WNT10A deficiency

BACKGROUND: The WNT10A protein is critical for the development of ectodermal appendages. Variants in the WNT10A gene may be associated with a spectrum of ectodermal abnormalities including extensive tooth agenesis. METHODS: In seven patients with severe tooth agenesis we identified anomalies in prim...

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Detalles Bibliográficos
Autores principales: Bergendal, Birgitta, Norderyd, Johanna, Zhou, Xiaolei, Klar, Joakim, Dahl, Niklas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122154/
https://www.ncbi.nlm.nih.gov/pubmed/27881089
http://dx.doi.org/10.1186/s12881-016-0349-4

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