Novel prokaryotic expression of thioredoxin-fused insulinoma associated protein tyrosine phosphatase 2 (IA-2), its characterization and immunodiagnostic application

BACKGROUND: The insulinoma associated protein tyrosine phosphatase 2 (IA-2) is one of the immunodominant autoantigens involved in the autoimmune attack to the beta-cell in Type 1 Diabetes Mellitus. In this work we have developed a complete and original process for the production and recovery of the...

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Detalles Bibliográficos
Autores principales: Guerra, Luciano Lucas, Faccinetti, Natalia Inés, Trabucchi, Aldana, Rovitto, Bruno David, Sabljic, Adriana Victoria, Poskus, Edgardo, Iacono, Ruben Francisco, Valdez, Silvina Noemí
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122161/
https://www.ncbi.nlm.nih.gov/pubmed/27881117
http://dx.doi.org/10.1186/s12896-016-0309-2

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