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Cutaneous Manifestations of Multiple Myeloma
Multiple myeloma (MM) is a proliferative disorder of plasma cells which produce abnormal immunoglobulin proteins. Skin involvement is rarely found in this disorder. They are either specific or nonspecific lesions. We report four such interesting patients who presented to us initially with common der...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122285/ https://www.ncbi.nlm.nih.gov/pubmed/27904188 http://dx.doi.org/10.4103/0019-5154.193682 |
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author | Behera, Binodini Pattnaik, Monali Sahu, Bharti Mohanty, Prasenjeet Jena, Swapna Mohapatra, Liza |
author_facet | Behera, Binodini Pattnaik, Monali Sahu, Bharti Mohanty, Prasenjeet Jena, Swapna Mohapatra, Liza |
author_sort | Behera, Binodini |
collection | PubMed |
description | Multiple myeloma (MM) is a proliferative disorder of plasma cells which produce abnormal immunoglobulin proteins. Skin involvement is rarely found in this disorder. They are either specific or nonspecific lesions. We report four such interesting patients who presented to us initially with common dermatoses such as leukocytoclastic vasculitis, pyoderma gangrenosum, and vesiculobullous disorders and were subsequently diagnosed to have MM. There were no skeletal involvements or renal function abnormality at the time of presentation. Unusual presentation, nonresponsiveness to conventional therapy, and abnormal blood parameters prompted us to suspect some underlying systemic conditions which were later confirmed to be MM after serum immunoelectrophoresis for M-band and bone marrow biopsy. |
format | Online Article Text |
id | pubmed-5122285 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-51222852016-11-30 Cutaneous Manifestations of Multiple Myeloma Behera, Binodini Pattnaik, Monali Sahu, Bharti Mohanty, Prasenjeet Jena, Swapna Mohapatra, Liza Indian J Dermatol Case Series Multiple myeloma (MM) is a proliferative disorder of plasma cells which produce abnormal immunoglobulin proteins. Skin involvement is rarely found in this disorder. They are either specific or nonspecific lesions. We report four such interesting patients who presented to us initially with common dermatoses such as leukocytoclastic vasculitis, pyoderma gangrenosum, and vesiculobullous disorders and were subsequently diagnosed to have MM. There were no skeletal involvements or renal function abnormality at the time of presentation. Unusual presentation, nonresponsiveness to conventional therapy, and abnormal blood parameters prompted us to suspect some underlying systemic conditions which were later confirmed to be MM after serum immunoelectrophoresis for M-band and bone marrow biopsy. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC5122285/ /pubmed/27904188 http://dx.doi.org/10.4103/0019-5154.193682 Text en Copyright: © Indian Journal of Dermatology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Case Series Behera, Binodini Pattnaik, Monali Sahu, Bharti Mohanty, Prasenjeet Jena, Swapna Mohapatra, Liza Cutaneous Manifestations of Multiple Myeloma |
title | Cutaneous Manifestations of Multiple Myeloma |
title_full | Cutaneous Manifestations of Multiple Myeloma |
title_fullStr | Cutaneous Manifestations of Multiple Myeloma |
title_full_unstemmed | Cutaneous Manifestations of Multiple Myeloma |
title_short | Cutaneous Manifestations of Multiple Myeloma |
title_sort | cutaneous manifestations of multiple myeloma |
topic | Case Series |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122285/ https://www.ncbi.nlm.nih.gov/pubmed/27904188 http://dx.doi.org/10.4103/0019-5154.193682 |
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