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Downregulation of miR-101 contributes to epithelial-mesenchymal transition in cisplatin resistance of NSCLC cells by targeting ROCK2

Chemoresistance and epithelial-mesenchymal transition (EMT) in cancer are linked phenomena. EMT contributes to chemoresistance, however, little is known about whether chemotherapy can induce EMT in cancer cells. Here, we found that miR-101 expression was downregulated in cisplatin-resistant non-smal...

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Detalles Bibliográficos
Autores principales: Ye, Zhiqiang, Yin, Shengli, Su, Zhongzhen, Bai, Mingjun, Zhang, Haibo, Hei, Ziqing, Cai, Songwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122329/
https://www.ncbi.nlm.nih.gov/pubmed/27229528
http://dx.doi.org/10.18632/oncotarget.6852